Phosphate Incorporation in Brain Phosphoinositides
نویسندگان
چکیده
منابع مشابه
LA Phosphate Incorporation in Brain Phosphoinositides *
To test this hypothesis, we have investigated the incorporation of radioactive inorganic phosphate into these phospholipids by rabbit brain slices. If the biosynthesis proceeds as formulated, I --f II + III, the following results can be predicted. Before equilibration of the labeled phosphorus, the phosphate groups in position 4 of II and positions 4 and 5 of 111 must have a higher radioactivit...
متن کاملLA Phosphate Incorporation in Brain
To test this hypothesis, we have investigated the incorporation of radioactive inorganic phosphate into these phospholipids by rabbit brain slices. If the biosynthesis proceeds as formulated, I --f II + III, the following results can be predicted. Before equilibration of the labeled phosphorus, the phosphate groups in position 4 of II and positions 4 and 5 of 111 must have a higher radioactivit...
متن کاملPhosphoinositides in the Flight Muscle of Periplaneta americana: Incorporation of Labelled Phosphate and Inositol
The content of phosphatidylinositol phosphate (DPI) in the flight musculature of the cockroach Periplaneta americana was found to be 30 nmol g ' wet weight, that of phosphatidylinositol-bis-phosphate (TPI) 6.5 nmol g wet weight. After administration of P-orthophosphate in vivo, the specific radioactiv ity (S.A.) of arginine phosphate reaches a plateau after 2 hours and remains constant for the...
متن کاملPhosphoinositides. 2. The inositol 1-phosphate structure in liver phosphatidylinositol.
The hydrolysis studies reported in the preceding paper (Hawthorne, 1960) suggest that in liver phosphatidylinositol the phosphate group is linked to one of the cis-hydroxyl groups of the inositol, i.e. to positions 1(3)or 2-. Until recently, the inositol monophosphate isolated from phosphoinositides was believed to be optically inactive (Iselin, 1949; Hawthorne, 1955) and so liver phosphatidyli...
متن کاملIncorporation of radioactive phosphate into the nucleic acids of brain slices.
The unequivocal incorporation of radioactive phosphate (32p) into the nucleic acids of brain slices has not as yet been demonstrated. Because of the great interest in the nucleic acids of the nervous system aroused by the work of Caspersson (1947) and Hyden (1943, 1947), it was decided to investigate the possible incorporation of 32p into the pentosenucleic acid (PNA) and deoxypentosenucleic ac...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1962
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)81358-8